Transcriptomics

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Understanding cancer drug resistance with Sleeping Beauty functional genomic screens: application to MAPK inhibition in cutaneous melanoma


ABSTRACT: To determine how VAV1 drives drug resistance to BRAFi, we overexpressed VAV1 in A375 and compared these cells to A375 overexpressing RAC1P29S. We also determined the impact of SRCi on the transcriptional program elicited by VAV1.

ORGANISM(S): Homo sapiens

PROVIDER: GSE226664 | GEO | 2023/03/09

REPOSITORIES: GEO

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