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PdgfrB signaling alters the beige adipogenic niche

ABSTRACT: Ageing beige adipose progenitor cells overexpress platelet derived growth factor receptor beta (PdgfrB) to prevent beige adipogenesis. Genetically deleting PdgfrB in restores beige adipocyte generation whereas activating PdgfrB in juvenile mice blocks beige fat formation.

ORGANISM(S): Mus musculus

PROVIDER: GSE226695 | GEO | 2023/03/06

REPOSITORIES: GEO

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