Transcriptomics

Dataset Information

0

 Preclinical development of brain permeable ERβ agonist for the treatment of glioblastoma


ABSTRACT: We examined the mechanisms by estrogen receptor beta agonist CIDD-0149897 regulates glioma progression. Glioma stem cells (GSCs) were treated with CIDD-0149897 , and total RNA was isolated for RNA-seq analysis. Our results demonstrated that treatment with CIDD-0149897 showed upregulation of apoptotic and p53 pathways and downregulates several pathways including MYC and E2F.

ORGANISM(S): Homo sapiens

PROVIDER: GSE226765 | GEO | 2023/09/18

REPOSITORIES: GEO

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