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E protein binding at the Tcra enhancer promotes Tcra repertoire diversity

ABSTRACT: The Tcra gene enhancer (Eα) is required for Tcra rearrangment. Our study assesses the role of E protein binding at Eα. Tcra repertoire sequencing was used to determine whether loss of Eα E protein binding sites alters recombination at Tcra.

ORGANISM(S): Mus musculus

PROVIDER: GSE227164 | GEO | 2023/03/16

REPOSITORIES: GEO

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E protein binding at the Tcra enhancer promotes Tcra repertoire diversity

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E protein binding at the <i>Tcra</i> enhancer promotes <i>Tcra</i> repertoire diversity.

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