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Effect of Omomyc on the in vitro growth of A375 human melanoma cell line

ABSTRACT: Skin melanomas are highly aggressive and metastatic. Omomyc is the best MYC inhibitor currently available. We analysed the effect of Omomyc expression in a transgenic and inducible (upon Doxycycline addition) manner in melanoma cells in vitro in A375 (mutated in BRAF) melanoma cell line. We used microarrays to detail the change in the gene expression programs induced by Omomyc on day 4.

ORGANISM(S): Homo sapiens

PROVIDER: GSE227840 | GEO | 2023/04/09

REPOSITORIES: GEO

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