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Comparison of hiPSCs, hESCs and fibroblasts

ABSTRACT: In our study, PRDM14 and NFRkB were found to enhance the reprogramming of human fibroblasts to hiPSCs in the presence of OCT4, SOX2, KLF4, with/without c-MYC (OSK/OSKC). To examnie if the obtained hiPSC share similar expression signature with hESC, we conducted the microarray analysis on the hiPSCs, hESCs and fibroblasts. The result showed that all of the examined hiPSCs resembled hESCs, but differed from fibroblasts MRC5.

ORGANISM(S): Homo sapiens

PROVIDER: GSE22792 | GEO | 2010/10/20

SECONDARY ACCESSION(S): PRJNA127815

REPOSITORIES: GEO

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Comparison of hiPSCs, hESCs and fibroblasts

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