Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression data from 3D spheroids of human amniotic epithelial stem cell (hAESC) treated with 20 uM Carnosic Acid

ABSTRACT: Gene expression profiling reveals multiple tissue-specific functionality of carnosic acid in a stem-based tool. We evaluated the effects of carnosic acid on human amniotic epithelial stem cells. We performed an untargeted whole-genome transcriptome analysis to explore functionality of carnosic acid in a stem cell-based tool.

ORGANISM(S): Homo sapiens

PROVIDER: GSE228408 | GEO | 2023/04/02

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Gene expression data from 3D spheroids of human amniotic epithelial stem cell (hAESC) treated with Tsuruazuki Extract (Tsuru)

Project description:Gene expression profiling reveals mesoderm lineage-specific genes were more significantly regulated with the most prominent regulated DEGs were identified in adipose tissue. We evaluated the effects of Tsuruazuki extract on human amniotic epithelial stem cells. We performed an untargeted whole-genome transcriptome analysis to explore functionality of Tsuru in a stem cell-based tool.

2024-09-30 | GSE278052 | GEO

Gene expression data from human adipose-derived stem cells (hASCs) treated with 20 uM oleacein

Project description:Gene expression profiling reveals multiple biological functions of oleacein. We evaluated the effects of oleacein on human adipose-derived stem cells. We performed an untargeted whole-genome transcriptome analysis to explore functionality of oleacein in a adipose stem cell-based tool.

2023-07-19 | GSE230619 | GEO

Gene expression data from 3D spheroids of human amniotic epithelial stem cell (hAESC) treated with 20 uM Carnosic Acid

Project description:Gene expression data from 3D spheroids of human amniotic epithelial stem cell (hAESC) treated with 20 uM Carnosic Acid

| PRJNA949643 | ENA

Gene expression data from diabetic human adipose-derived stem cells (d-hASC) treated with 1uM oleacein

Project description:Gene expression profiling reveals multiple biological functions of oleacein in diabetic model. We evaluated the effects of oleacein on diabetic human adipose-derived stem cells. We performed an untargeted whole-genome transcriptome analysis to explore functionality of oleacein in a diabetic adipose stem cell-based tool.

2023-07-19 | GSE230618 | GEO

Transcriptome of amniotic fluid in vervet monkey

Project description:Transcriptomic profiling is a crucial tool for understanding growth, development, behavior and predisposition to diseases and the development of health biomarkers. Here, we demonstrate the feasibility of transcriptomic assessment of cell-free fetal RNA in vervet monkey amniotic fluid supernatant (AFS).

2019-09-13 | GSE119908 | GEO

Proteomic profiling of the human amniotic stem cell-secreted proteins

Project description:In this study, the expression profiles of secreted proteins from amniotic mesenchymal stem cells (AMSCs) and amniotic epithelial cells (AECs) were comprehensively analyzed utilizing mass spectrometry-based proteomics.

2024-11-18 | PXD057076 | Pride

U373MG edaravone and carnosic acid

Project description:We investigated the gene expression profiles of U373MG human astrocytoma cells treated with vehicle (DMSO) or edaravone or carnosic acid) or both edaravone and carnosic acid. Edaravone is a free radical scavenger sold as radicut. Carnosic acid is a phytochemical found in rosemary and sage.

2019-04-30 | GSE129001 | GEO

Global Gene Expression Analysis of Term Amniotic Fluid Cell-Free Fetal RNA

Project description:The objective of this study was to identify the tissue expression patterns and biological pathways enriched in term amniotic fluid cell-free fetal RNA by comparing functional genomic analyses of term and second-trimester amniotic fluid supernatants. There were 2,871 significantly differentially regulated genes. In term amniotic fluid, tissue expression analysis showed enrichment of salivary gland, tracheal, and renal transcripts as compared with brain and embryonic neural cells in the second trimester. Functional analysis of genes upregulated at term revealed pathways that were highly specific for postnatal adaptation such as immune function, digestion, respiration, carbohydrate metabolism, and adipogenesis. Inflammation and prostaglandin synthesis, two key processes involved in normal labor, were also activated in term amniotic fluid. This was a prospective whole genome microarray study comparing eight amniotic fluid samples collected from eight women at term who underwent prelabor cesarean delivery and eight second-trimester amniotic fluid samples from routine amniocenteses. A functional annotation tool was used to compare tissue expression patterns in term and second-trimester samples. Pathways analysis software identified physiologic systems, molecular and cellular functions, and upstream regulators that were significantly overrepresented in term amniotic fluid.

2013-04-23 | E-GEOD-46286 | biostudies-arrayexpress

Amniotic fluid-derived cells: genome-wide expression in early and late cultures

Project description:Amniotic fluid stem cells (AFSCs) are of interest in regenerative medicine as a non-controversial and potentially 'abundant' source of stem cells. Progress has been made in understanding amniotic fluid stem cell biology, and amniotic fluid-derived cells have been induced to form neurons, osteoblasts, muscle cells, and others. Our study evaluates change in the genome-wide expression profile of amniotic fluid stem cells during in-vitro culture, using Affymetrix U133 Plus 2.0 microarray chips. We found that only 3.08% of gene probes were differentially expressed from early to late passage of AFSC culture. The differentially expressed genes were related to biological processes or cellular function - including transcription factors, protein kinases, and cytokines/growth factors. Other gene-sets of interest were oncogenes and tumor suppressor genes, which were a very small number of genes. We further analyzed the gene sets of interest using NIH DAVID and GSEA bioinformatics databases for gene annotations analysis. Applying false discovery rate correction, there was no significant difference in the genome-wide expression profiling between early and late passage. AFSCs maintain their genome-wide expression profile during in-vitro culture. Amniotic fluid-derived c-kit-positive cells were maintained in stem cell culture and genome-wide expression changes were studied and compared between early passage and late passage in culture.

2012-08-02 | E-GEOD-39839 | biostudies-arrayexpress

Proteomic analysis of human Wharton's jelly mesenchymal stem cells and human amniotic epithelial stem cells: a comparison of therapeutic potential

Project description:proteomics analysis of human umbilical cord mesenchymal stem cells and human amniotic epithelial stem cells

2024-06-05 | PXD052844 |