Genomics

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CTCF ChIP-seq in NSCs


ABSTRACT: Both Smchd1 deletion and its MommeD43 mutant version cause loss of long-range chromatin interactions in NSCs and a strengthening of more local interactions. We assayed CTCF binding in the relevant genotypes to see if this is related to altered CTCF binding. ChIP-seq using an anti-CTCF antibody to check if chromatin binding of CTCF is altered in Smchd1MD43-GFP/MD43-GFP and Smchd1del/del neural stem cells (NSCs) compared to Smchd1GFP/GFP NSCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE228672 | GEO | 2023/04/04

REPOSITORIES: GEO

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