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Gene expression profile of overgrown livers from genetic models involving YAP or MYC overexpression.

ABSTRACT: We reasoned that when livers grow beyond their normal size, some growth regulating secreted factors will be suppressed and others will be overexpressed. To obtain overgrown livers, we used genetic models involving YAP or MYC overexpression We the identified differentially expressed genes in both models and filtered out secreted factors by bioinformatically defined secreted protein list.

ORGANISM(S): Mus musculus

PROVIDER: GSE228863 | GEO | 2024/04/01

REPOSITORIES: GEO

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Gene expression profile of overgrown livers from genetic models involving YAP or MYC overexpression.

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