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Physical activity regulates the immune response to breast cancer by a hematopoietic stem cell-autonomous mechanism

ABSTRACT: To investigate the role of physical activity in the regulation of tumor incidence, we performed differential gene expression analysis on tumors from sedentary (SED) and phsyically active (PA) mice at an early (week12) and late (week18) stage of tumor development. We also performed differential gene expression analysis on hematopoietic stem cells (HSCs) from SED and PA mice, as well as from SED mice transplanted with PA HSCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE229575 | GEO | 2023/09/30

REPOSITORIES: GEO

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Gene expression data from 16-month and 3-month old male rats, with three different levels of activity over the life span: sedentary, twice weekly physical activity, regular running wheel exercise.

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