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The tumor suppressive role of ANCO1 in early-stage triple-negative breast cancer [RNA-seq]

ABSTRACT: To understand the impact of ANCO1 reduction on gene expressions, we performed RNA-seq experiments in shANCO1 and shCTRL MCF10A and MCFDCIS cells in 2D and 3D culture. We report ANCO1 knockdown leads to altered gene expression profiles. Enriched gene sets including chr1q21.3 and mTORC1 signaling may be responsible for phenotypical changes in shANCO1 cell lines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE230062 | GEO | 2023/07/31

REPOSITORIES: GEO

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