Transcriptomics

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Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease


ABSTRACT: We developed novel chemically defined recipe media named NPSR-v2, that was capable of expanding mouse and human nephron progenitor cells (NPC) for long term culture in vitro in 2D (2 Dimension) format. NPSR-v2 and these expanded NPC can be used for versatile application, such as reprograming, whole genome-wide CRISPR screen, kidney-associated disease modeling and library drug screening etc.

ORGANISM(S): synthetic construct Mus musculus Homo sapiens

PROVIDER: GSE230707 | GEO | 2024/03/14

REPOSITORIES: GEO

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