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SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway [Larval SLAM-Itseq]

ABSTRACT: We investigated the immediate transcriptional changes in hepatocytes following APAP-induced acute liver injury by exposing lf:UPRT zebrafish larvae to DMSO or APAP in the presence of 4TU. We the performed gene expression profiling analysis on total and nascent counts using data obtained from SLAM-ITseq of WT and Nrf2KO animals.

ORGANISM(S): Danio rerio

PROVIDER: GSE230831 | GEO | 2024/01/13

REPOSITORIES: GEO

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To investigate 4-TU labelling kinetics in a novel zebrafish transgenic line (lf:UPRT). [Adult SLAM-Itseq]

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SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway [Larval SLAM-Itseq]

Project description:SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway [Larval SLAM-Itseq]

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SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway

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