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Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy [kdSdc1_RNAseq]

ABSTRACT: To investigate the function of SDC1 in the regulation of anti-tumor immunity, we established B16 cell lines in which sdc1 or control RNA has been knocked down by shRNA. Then the cells were stimulated with or without IFNγ. We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different groups, each group included three replicates.

ORGANISM(S): Mus musculus

PROVIDER: GSE231355 | GEO | 2024/09/18

REPOSITORIES: GEO

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Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy (kdSdc1 and mutant)

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Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy [kdSdc1_scRNAseq]

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Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy

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Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy

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Inhibition of PARP14 restores response to α-PD1 immune checkpoint inhibition in tumours with resistance driven by IFNγ. PARP14 study.

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Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy [kdSdc1_scRNAseq]

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Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy [kdSdc1_RNAseq]

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Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy.

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