Genome wide (GW) and validation CRISPR screens on encephalitogenic CD4+ T cell migration into the CNS
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ABSTRACT: To identify genes driving encephalitogenic CD4+ T cell migration into the CNS, we performed a genome-wide CRISPR screen and a subsequent validation screen For the genome-wide CRISPR screen, up to 4 sgRNA per gene and 800 non targeted controls were included, for a total of 87690 individual sgRNAs, and for the validation screen, up to 6 sgRNA per gene and 241 non targeted controls for a total of 12000 individual sgRNAs
ORGANISM(S): synthetic construct Rattus norvegicus
PROVIDER: GSE232340 | GEO | 2023/08/01
REPOSITORIES: GEO
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