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Responsiveness of hypomethylated and control tumor cells to canonical Wnt-signalling

ABSTRACT: During metastasis, cancer cells travel the circulation to colonize distant sites. Due to the rarity of these events, the immediate cell fate decisions of metastasizing tumor cells (mTC) are poorly understood and the role of the endothelium, as dissemination interface, remains elusive. Using a novel combinatorial mTC enrichment approach, we provide a first transcriptional blueprint of the early colonization process

ORGANISM(S): Mus musculus

PROVIDER: GSE232855 | GEO | 2023/10/02

REPOSITORIES: GEO

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