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Development of gene expression signatures for high glucose-induced renal tubular fibrosis

ABSTRACT: To further explore differentially expressed genes in high glucose-induced renal tubular fibrosis cells, we used whole transcriptome microarray expression profiling as a discovery platform to identify genes with a potential role in the high glucose-induced renal fibrosis process. Low-glucose stimulation (5.5 mM glucose) and high-glucose stimulation (25 mM glucose) of human renal tubular HK2 cells identified a consensus profile of 644 highly expressed genes to distinguish high-glucose fibrotic renal tubules from control samples.

ORGANISM(S): Homo sapiens

PROVIDER: GSE232913 | GEO | 2024/06/30

REPOSITORIES: GEO

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