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Multiomics approach reveal novel insights in FUS driven Juvenile Amyotrophic Lateral Sclerosis: a family quartet analysis

ABSTRACT: We have identified a novel de novo variation in FUS gene in a sporadic juvenile ALS patient. FUS is an RNA-binding protein actively involved in various aspect of nucleic acid metabolism. We performed RNA-seq to identify altered transcriptome in juvenile ALS.

ORGANISM(S): Homo sapiens

PROVIDER: GSE232929 | GEO | 2024/05/25

REPOSITORIES: GEO

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