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Gene expression and chromatin accessibility profile at single cell level of B16 cells [B16_D0_3_5_scMulti]

ABSTRACT: B16 F10 is a depigmented mouse melanoma cell line which is considered as a homogeneous cell population. These cells when cultured at a very low density of 100 cells/cm2 starts to pigment progressively. We used single nucleus RNA+ATAC sequencing (scMultiomics) to analyze the transciptional diversity and to investigate the epigenetic basis of this diversity of day 0, 3 and 5 B16 cells cultured at low density.

ORGANISM(S): Mus musculus

PROVIDER: GSE233134 | GEO | 2024/07/05

REPOSITORIES: GEO

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Gene expression profile at single cell level of low and high pigmented B16 cells [B16_D7_LP_HP_scRNA]

Project description:B16 F10 is a depigmented mouse melanoma cell line which is considered as a homogeneous cell population. These cells when cultured at a very low density of 100 cells/cm2 starts to pigment progressively for a period of 7 days. Phenotypically two broad population of low and high pigmented cells are observed at day 7 in this low density culture. We used single cell RNA sequencing (scRNA-seq) to analyze the diversity of B16 cells cultured at low density for 7 days.

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