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Synapse related gene expression is downregulated in SPG7 patient induced pluripotent stem cell derived cortical neurons

ABSTRACT: To understand the disease mechanism of SPG7 hereditary spastic paraplegia, we generated and evaluated patient and control induced pluripotent stem cell derived cortical neurons. We then performed gene expression profiling analysis using data obtained from RNA-seq.

ORGANISM(S): Homo sapiens

PROVIDER: GSE233258 | GEO | 2023/05/30

REPOSITORIES: GEO

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