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An integrative single-cell multiomics profiling of human pancreatic islets identifies T1D associated genes, regulatory regions, and single nucleotide polymorphism [ATAC-seq]

ABSTRACT: To investigate the mechanism of DLK1 and RASGRP1 knockout in inducing beta cell apoptosis, we performed chromatin access profiling analysis using data obtained from ATAC-seq of DLK1 WT vs DLK1-/- and RASGRP1 WT VS RASGRP1-/- hPSCs differentiated beta cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE233474 | GEO | 2023/11/13

REPOSITORIES: GEO

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An integrative single-cell multiomics profiling of human pancreatic islets identifies T1D associated genes, regulatory regions, and single nucleotide polymorphism [bulk RNA-seq]

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