Impaired age-associated mitochondrial translation is mitigated by exercise and PGC-1α
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ABSTRACT: To investigate age-related changes in muscle mitochondrial proteostasis, as well as the effect of higher and lower levels of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) in this paradigm, we isolated RNA from M. gastrocnemius muscle tissue of muscle-specific PGC-1α gain- and loss-of-function mouse models, at the ages of three and twenty four months.
ORGANISM(S): Mus musculus
PROVIDER: GSE233485 | GEO | 2023/08/04
REPOSITORIES: GEO
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