Transcriptomics

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RNA sequencing of an optimized shuttle cell line for intranasal delivery


ABSTRACT: We generated cell lines from LX-2 hepatic stellate cells that are otpimzed for intranasal delivery of the oncolytic adenovirus XVir-N-31 to treat glioblastoma. One cell line migrates faster, the next in addition expressed HSV-TK as a safety gene to eliminate cells in case of adverse events.

ORGANISM(S): Homo sapiens

PROVIDER: GSE234262 | GEO | 2023/08/18

REPOSITORIES: GEO

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