Single nuclei RNAseq of the periosteal response to bone fracture in mice
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ABSTRACT: Bone regeneration is a highly efficient process allowing scarless healing after injury. The periosteum, the outer layer of bones, is a critical source of skeletal stem/progenitor cells (SSPCs), as well as immune, endothelial and neural cells during bone repair. In our study, we generated a single-nuclei atlas of the murine periosteal response to bone fracture. We generated single nuclei datasets from uninjured periosteum and from injured periosteum and hematoma/fracture callus at days 5 and 7 post-injury from wild-type mice.
ORGANISM(S): Mus musculus
PROVIDER: GSE234451 | GEO | 2024/04/01
REPOSITORIES: GEO
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