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Loss of DNA glycosylases promotes health span/neuroprotection in a C. elegans model of human tauopathy

ABSTRACT: We utilized a Caenorhabditis elegans (C. elegans) model of human tauopathy to investigate the role of DNA glycosylases (Ung-1 and Nth-1 knockout worms) in disease development and progression. We then performed gene expression profiling analysis using data obtained from RNA-seq of 12 different genotypes grown under normal conditions.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE235015 | GEO | 2024/10/23

REPOSITORIES: GEO

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