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Single Cell Transcriptomic Analysis in a Mouse Model of Barth Syndrome Reveals Cell-Specific Alterations in Gene Expression and Intercellular Communication

ABSTRACT: To identify novel, cell-specific, pathological pathways that mediate heart dysfunction in Barth Syndrome, we performed single-nucleus RNA-sequencing (snRNA-seq) on wild type and Tafazzin-knockout mouse hearts.

ORGANISM(S): Mus musculus

PROVIDER: GSE235047 | GEO | 2023/06/20

REPOSITORIES: GEO

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