Transcriptomics

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RNA-Sequencing of Saliva Samples from COVID-Infected and Vaccinated Subjects


ABSTRACT: SARS-CoV-2 virus is known to infect the oral cavity and can be readily detected using PCR-based testing. In this study, we examined the host transcriptomic response to PCR-confirmed SARS-CoV-2 virus infection, vaccination against SARS-CoV-2, or breakthrough infection following vaccination using RNA-sequencing. The identification of the viral variant for all samples was obtained using full viral genome sequencing. Approximately equal numbers of males and females were used for every major variant lineage. Results indicate strong anti-viral responses in each case, with some differences due to variant strain and vaccination history, as well as age and sex.

ORGANISM(S): Homo sapiens

PROVIDER: GSE235262 | GEO | 2023/09/19

REPOSITORIES: GEO

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