Methylation profiling

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DNA methylation profiling of blood from healthy Australian donors


ABSTRACT: We assessed DNA methylation in whole blood samples from an Australian population across different age groups. Our study focused on evaluating the accuracy of DNA methylation age estimation using the Horvath 2018 and PhenoAge clocks. Additionally, we examined previously reported functional measures of aging in peripheral blood mononuclear cells (PBMCs). Our findings indicated that DNA methylation age effectively predicted donor age, while only a limited number of tested cell functions showed correlations with donor age.

ORGANISM(S): Homo sapiens

PROVIDER: GSE235717 | GEO | 2023/09/15

REPOSITORIES: GEO

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