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Enhanced crosslinking and immunoprecipitation analysis of human fetal β-cells

ABSTRACT: N6-methyladenosine (m6A) is the most abundant chemical modification in mRNA, and plays important roles in human embryonic stem cell pluripotency, maintenance, and differentiation. However, the role of m6A and the precise mechanisms involved during the development of β-cells are unexplored. Here, we performed enhanced crosslinking and immunoprecipitation (eCLIP) assays to identify m6A sites regulated by METTL14 in EndoC-βh1 human fetal β-cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE236324 | GEO | 2024/06/13

REPOSITORIES: GEO

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