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Small RNA-seq gene expression profile of the SUM159PT breast cancer cell line, upon overexpression of the microRNA responsive elements of candidate TDMD triggers (ABCA1, HADHB, TRAF6)

ABSTRACT: We investigate the potential of candidate microRNA responsive elements (MRE, contained in the 3'UTR of candidate transcripts) to trigger target-dependent microRNA degradation (TDMD). To this purpose, we over-expressed the MRE by delivering a lentiviral construct in SUM159PT cells and we profiled microRNAs by small RNA sequencing 7 days after the infection.

ORGANISM(S): Homo sapiens

PROVIDER: GSE236781 | GEO | 2024/12/31

REPOSITORIES: GEO

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small RNA-seq gene expression profile of the SUM159PT breast cancer cell line, upon overexpression of the microRNA responsive elements of candidate TDMD triggers (ABCA1, HADHB, TRAF6)

Project description:small RNA-seq gene expression profile of the SUM159PT breast cancer cell line, upon overexpression of the microRNA responsive elements of candidate TDMD triggers (ABCA1, HADHB, TRAF6)

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