Phage-Antibiotic Combinations Against Klebsiella pneumoniae
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ABSTRACT: hvKP ATCC43816 and its lytic phage H5 were employed as a phage-antibiotic combination model. Based on the comprehensive characterization of phages, including cryo-electron microscopy, we evaluated the synergic effect of H5 on bacterial killing in vitro when combined with multiple antibiotics, and analyzed the advantages of phage-antibiotic combinations from an evolutionary perspective and proposes a novel PAS mechanism by using ceftazidime as an example.
ORGANISM(S): Klebsiella pneumoniae subsp. pneumoniae
PROVIDER: GSE237490 | GEO | 2023/09/14
REPOSITORIES: GEO
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