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Response of osteoblasts on amine-based polymer coatings cor-relates with the amino group density

ABSTRACT: The integration of implants can be improved by physical but mainly by chemical modifications of the implant surface. It has already been shown that amine-based coatings improve cell attachment, cell migration, and intracellular signaling. The aim of this study was to determine the role of the amino group density in this positive cell response by developing controlled amino-rich nano-layers. Using Clariom S microarrays to perform genome-wide expression profilng, changes in adhesion related genes after cultivation of osteoblast-like cells on an amino group-rich coating could be seen.

ORGANISM(S): Homo sapiens

PROVIDER: GSE237945 | GEO | 2023/10/04

REPOSITORIES: GEO

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