Transcriptomics

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Gene expression profiling of asbestos-related lung squamous cell carcinoma


ABSTRACT: To identify gene expression biomarkers associate with asbestos-related lung squamous cell carcinoma, we analyzed gene expression profiles for a total of 56 lung squamous cell carcinomas using 44K Illumina Gene Expression microarrays. Twenty-six cases had lung asbestos body counts above levels associated with urban dwelling (ARLC-SCC: asbestos-related lung cancer-squamous cell carcinoma) and 30 cases had no lung asbestos bodies (NARLC-SCC: non-asbestos related lung cancer- squamous cell carcinoma). Genes differentially expressed between ARLC-SCC and NARLC-SCC were identified on fold change and P-value, and then prioritised using gene ontology.

ORGANISM(S): Homo sapiens

PROVIDER: GSE23822 | GEO | 2012/01/30

SECONDARY ACCESSION(S): PRJNA130571

REPOSITORIES: GEO

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