Transcriptomics

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YTHDF1 deletion in macrophages aggravates LPS-induced inflammation


ABSTRACT: To investigate the effect of YTHDF1 on LPS-induced inflammation, we performed RNA-seq with the total RNA extracted from peritoneal macrophages (PMs) with or without YTHDF1 deletion. Ythdf1-/- or wild type mice were intraperitoneally injected with 6% starch broth. Three days later, PMs were isolated and cultured overnight. Then, the PMs were treated by LPS (1 μg/mL) or PBS for 6 hours, followed by RNA extraction and RNA-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE238236 | GEO | 2023/08/08

REPOSITORIES: GEO

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