Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer [Ets1 ATAC-Seq]
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ABSTRACT: The gene regulatory network (GRN) underlying CTL differentiation and whether Tex responses can be functionally reinvigorated are incompletely understood. Here, we systematically mapped causal GRNs via single-cell CRISPR (scCRISPR) screens in vivo and discovered checkpoints for CTL differentiation.
ORGANISM(S): Mus musculus
PROVIDER: GSE239801 | GEO | 2023/11/15
REPOSITORIES: GEO
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