Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression profile in the livers of insulin-resistant mice treated with all-trans retinoic acid

ABSTRACT: Therapeutic effect of all-trans retinoic acid on diet-induced insulin resistance was found. To explore molecules involved in this pharmacological effect, the hepatic transcriptome was analyzed.

ORGANISM(S): Mus musculus

PROVIDER: GSE24096 | GEO | 2013/09/12

SECONDARY ACCESSION(S): PRJNA130295

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Gene expression profile in the livers of insulin-resistant mice treated with all-trans retinoic acid

Project description:Therapeutic effect of all-trans retinoic acid on diet-induced insulin resistance was found. To explore molecules involved in this pharmacological effect, the hepatic transcriptome was analyzed. RNA samples were prepared from the liver biopsies of control, HFHFr-N, HFHFr-NA, HFHFr-F, and HFHFr-FA groups (five mice in each group). The samples were pooled and analyzed using Whole Mouse Genome Microarray 4x44K (G4122F).

2013-09-12 | E-GEOD-24096 | biostudies-arrayexpress

Clinical Trial of All-trans-retinoic Acid, Bevacizumab and Atezolizumab in Colorectal Cancer

Project description:The main purpose of this clinical trial is to learn about the good and the bad effects of all trans retinoic acid (ATRA), atezolizumab and bevacizumab as a possible treatment for advanced colorectal patients. Participants will be treated with the following combination of these drugs: 1. ATRA will be given in a pill form to be taken twice a day at home for 7 days starting on day 1 of a cycle. 2. Atezolizumab will be given through a vein in arm or through mediport over 60-90 minutes every 2 weeks in the outpatient chemotherapy infusion centers at UTSW. 3. Bevacizumab will be given through a vein in arm or through mediport over 20-40 minutes every 2 weeks in the outpatient chemotherapy infusion centers at UTSW.

| 70824 | ecrin-mdr-crc

Transcription profiling of F9 teratocarcinoma sublines characterized by the presence or absence of the RAR gamma nuclear retinoic acid receptor treated with trans retinoic acid and the novel retinoid, ST1926

Project description:Effect of all trans retinoic acid and the novel retinoid, ST1926, on the profile of gene expression in F9 teratocarcinoma sublines characterized by the presence or absence of the RAR gamma nuclear retinoic acid receptor

2005-12-31 | E-MEXP-361 | biostudies-arrayexpress

Gene expression changes in mouse neuroepithelial organoids in response to all-trans retinoic acid.

Project description:We describe the transcriptomic changes in neuroepithelial organoids in response to all-trans retinoic acid.

2022-10-01 | GSE214368 | GEO

All-Trans-Retinoic Acid Treatment of IDH Mutant Astrocytes

Project description:All-Trans-Retinoic Acid Treatment of IDH Mutant Astrocytes

| PRJNA1061109 | ENA

All-Trans-Retinoic Acid Treatment of IDH Mutant Astrocytes

Project description:All-Trans-Retinoic Acid Treatment of IDH Mutant Astrocytes

| PRJNA721930 | ENA

Combination treatmetn of MRT68921 and all-trans retinoic acid in HL-60 human leukemia cells

Project description:It was previously reported that inhibition of autophagosome formation by MRT68921 induced accumulation of cytosolic dsDNA, which can activate cytosolic DNA-sensor signaling pathway, thereby reducing cell viability through reactive oxygen species generation in leukemia cells. Thus, we examined the effect of combination treatment of MRT68921 and a leukemia differentiation therapeutic drug, all-trans retinoic acid.

2024-03-05 | GSE193056 | GEO

RIME against PBX1 protein in P19.6 mouse embryonal carcinoma cells treated for 48 hours with all-trans retinoic acid

Project description:Identification of PBX1 interactors in P19.6 mouse embryonal carcinoma cells treated for 48 hours with all-trans retinoic acid.

2017-04-03 | PXD006158 | Pride

Hepatic gene expression data from mice injected with all-trans-retinoic acid

Project description:Mice were given an intraperitoneal injection of a pharmacologic dose of all-trans-retinoic acid or vehicle control and liver tissue was collected 4 hours post-injection. RNA was extracted from liver samples and used in microarray analysis.

2020-10-06 | E-MTAB-9396 | biostudies-arrayexpress

All-trans retinoic acid effect on the squamous cell carcinoma cell line ME180: time course

Project description:All-trans retinoic acid (ATRA) has been shown to have anti-proliferative effects, particularly in the context of cancer. However, the effects of ATRA on gene and microRNA expression in solid tumors have not been investigated. In this study, we performed gene expression and microRNA analysis of the squamous cell carcinoma cell line, ME180, following treatment with 10 micromolar all-trans retinoic acid (ATRA) for 1, 3, and 6 hours. Results provide insight into the temporal regulation of genes and microRNAs by retinoids.

2014-08-01 | GSE54464 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data