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Epigenome analysis of anterior capsular membrane of lens in healthy and cataract patients

ABSTRACT: DNA methylation levels were analyzed by MethylationEPIC BeadChip (850K) in ARC patients and normal controls. Compared with the control group, a total of 52705 differentially methylated site (DMS) were detected in the ARC group, of which 13858 were hypermethylated and 38847 were hypomethylated. Our study revealed that the whole-genome DNA methylation patterns and gene expression profiles in ARC and identifified molecular markers of methylation may aid in the prevention, diagnosis, treatment, and prognosis of ARC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE241767 | GEO | 2024/08/27

REPOSITORIES: GEO

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