Long read transcriptome sequencing of ccRCC tumour cell line RCC4
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ABSTRACT: Clear cell renal cell carcinoma (ccRCC) is the most common form of kidney cancer. To date, long-read RNA sequencing has not been applied to kidney cancer. Here, we used ONT long-read Direct RNA sequencing to profile the transcriptomes of ccRCC cell line RCC4, with and without exposure to pro-inflammatory cytokines. Our results revealed differentially expressed genes induced by the pro-inflammatory cytokines. Moreover, results here revealed potential tumour origin of novel isoforms and genes that were discovered in the archival tumour samples by long-read sequencing.
ORGANISM(S): Homo sapiens
PROVIDER: GSE242084 | GEO | 2023/09/04
REPOSITORIES: GEO
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