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Differential early pathogenic changes in human ileal gene expression in Crohn's disease and ulcerative colitis

ABSTRACT: The aim of this study is to identify early pathogenic changes in ileal gene expression that precede the development of macroscopic disease in inflammatory bowel diseases (IBDs). We focused on two IBD phenotypes that were unlikely to overlap: 1) ileal Crohn’s disease (CD) patients undergoing initial ileocolic resection of diseased ileum; and 2) ulcerative colitis (UC) patients undergoing total colectomy. The Control patients were those patients without IBD undergoing initial right hemicolectomy or total colectomy.

ORGANISM(S): Homo sapiens

PROVIDER: GSE24287 | GEO | 2010/09/26

SECONDARY ACCESSION(S): PRJNA129995

REPOSITORIES: GEO

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Differential early pathogenic changes in human ileal gene expression in Crohn's disease and ulcerative colitis

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