Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Essential role of macrophages in contact hypersensitivity-induced hair regeneration

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Mus musculus

PROVIDER: GSE243089 | GEO | 2024/05/08

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Essential role of macrophages in contact hypersensitivity-induced hair regeneration [DPCP vs control]

Project description:This work demonstrates that contact hypersensitivity exerts a direct stimulatory effect on hair follicles to fasten anagen entry. The stimulatory effect on hair growth is mediated by macrophages.

2024-05-08 | GSE243088 | GEO

Essential role of macrophages in contact hypersensitivity-induced hair regeneration [Clod vs Encap]

2024-05-08 | GSE243087 | GEO

Essential role of macrophages in contact hypersensitivity-induced hair regeneration

Project description:Essential role of macrophages in contact hypersensitivity-induced hair regeneration

| PRJNA1016339 | ENA

Essential role of macrophages in contact hypersensitivity-induced hair regeneration [DPCP vs control]

Project description:Essential role of macrophages in contact hypersensitivity-induced hair regeneration [DPCP vs control]

| PRJNA1016352 | ENA

Essential role of macrophages in contact hypersensitivity-induced hair regeneration [Clod vs Encap]

Project description:Essential role of macrophages in contact hypersensitivity-induced hair regeneration [Clod vs Encap]

| PRJNA1016353 | ENA

Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration

Project description:This SuperSeries is composed of the SubSeries listed below.

2021-02-19 | GSE159939 | GEO

p63+/Krt5+ Distal Airway Stem Cells are Essential for Lung Regeneration

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-11-20 | E-GEOD-60849 | biostudies-arrayexpress

Array analysis of wound induced hair neogenesis

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-08-05 | E-GEOD-50420 | biostudies-arrayexpress

Discovery of neuro- and vascular-associated periosteum-resident macrophages essential for cortical bone regeneration

Project description:This SuperSeries is composed of the SubSeries listed below.

2024-06-01 | GSE190485 | GEO

The role of platelets in leukocyte recruitment in chronic contact hypersensitivity induced by repeated elicitation.

Project description:Platelets have been shown to be important in inflammation, but their role in chronic allergic dermatitis remains unclear. To investigate the role of platelets in a mouse model of chronic contact hypersensitivity induced by repeated elicitation, mice were sensitized and repeatedly elicited in ears with hapten, with or without platelet depletion, by administering antiplatelet antibody or busulfan. Ear thickness, leukocyte infiltration, serum IgE, and scratching behavior significantly decreased in thrombocytopenic mice. cDNA microarray of ear tissue showed reduced gene expression associated with Th2 lymphocytes. Flow cytometry showed increased P-selectin expression on platelets and an increased number of platelet-leukocyte aggregates in blood of repeatedly elicited mice, compared with sham-sensitized mice. In thrombocytopenic mice, inflammation was restored by platelet infusion, which was blocked by platelets from P-selectin-deficient mice or by pretreating platelets with anti-P-selectin antibody. Moreover, injection of activated platelet supernatant into ears led to increased leukocyte infiltration, which was blocked by pretreating platelets with antiplatelet compounds or neutralizing several chemokines in the platelet supernatant. These results suggest that platelets induce leukocyte recruitment into skin by forming platelet-leukocyte aggregates via P-selectin in blood and secreting chemokines at inflamed sites. Therefore, controlling platelet activity may be useful for treatment of chronic allergic dermatitis.

| S-EPMC1899463 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data