Transcriptomics

Dataset Information

0

The gene expression profiles of leukemia cells isolated from spleens of CreMx-1;CPSF6-RARG mice and Wt1F/+CreMx-1;CPSF6-RARG mice


ABSTRACT: We found that CPSF6-RARG fusion gene drives the aberrant expansion of HSCs and progenitor cells, which may lead to a preleukemic phenotype. Moreover, wt1 haploinsufficiency cooperates with RARG fusions to induce AML. To investigate the mechanism by which Wt1 haploinsufficiency cooperates with RARG fusion overexpression to induce AML in vivo, we analyzed the gene expression profiles of leukemia cells isolated from CreMx-1;CPSF6-RARG mice and Wt1F/+CreMx-1;CPSF6-RARG mice through RNA-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE243415 | GEO | 2024/10/15

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2024-10-16 | GSE275303 | GEO
2024-10-16 | GSE275304 | GEO
2024-10-15 | GSE243437 | GEO
2024-10-24 | GSE243817 | GEO
2024-10-24 | GSE247606 | GEO
2024-10-24 | GSE273551 | GEO
2024-10-24 | GSE245012 | GEO
2024-10-24 | GSE273550 | GEO
2024-10-24 | GSE245028 | GEO
| PRJNA1018491 | ENA