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A widespread cell atlas of pig skin from embryonic development to postnatal aging

ABSTRACT: Skin is the largest barrier organ with complex structure and function. We investigated the transcriptional dynamics of pig skin during development and aging at single-cell resolution. Using single-cell RNA sequencing, we profiled the transcriptomes of 443,529 skin cells derived from 30 individuals of 10 developmental time points staged between 56 days of gestation and 7 years old. Our analysis identified the dynamic changes in the cellular transcriptional profile of eight skin cell types at different developmental stages, exhibiting time-dependent skin cell heterogeneity.

ORGANISM(S): Sus scrofa

PROVIDER: GSE244532 | GEO | 2024/08/31

REPOSITORIES: GEO

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