Transcriptomics

Dataset Information

0

An integrated toolkit for human microglia functional genomics


ABSTRACT: Microglia, the brain’s resident immune cells, play vital roles in brain development, and disorders like Alzheimer’s disease (AD). Human iPSC-derived microglia (iMG) provide a promising model to study these processes. However, existing iMG generation protocols face challenges, such as prolonged differentiation time, lack of detailed characterization, and limited gene function investigation via CRISPR-Cas9. In this study will generated iMG from human iPSCs using our newly developed protocol. We used single cell RNA-Seq to study the transcriptomic profiles of our newly formed iMG. The single cell RNA-Seq data under this accession is from wild type iMG (Hashtag 7) and OTHER KO iMG (Hashtag 8)

ORGANISM(S): Homo sapiens

PROVIDER: GSE244653 | GEO | 2024/04/17

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2020-05-14 | GSE129630 | GEO
2021-04-08 | GSE163984 | GEO
| PRJNA1023967 | ENA
2023-05-17 | GSE173180 | GEO
2023-10-18 | GSE245309 | GEO
| PRJNA1099173 | ENA
| PRJNA719151 | ENA
2021-05-29 | E-MTAB-10323 | biostudies-arrayexpress
| S-EPMC11005142 | biostudies-literature
2021-05-12 | GSE174231 | GEO