Transcriptomics

Dataset Information

0

Gene expression profiles at the single cell levels of murine airway T helper cells challenged with dog allergens


ABSTRACT: We established a mouse model of dog allergy by repeatedly administering dog dander and epithelium extracts via the intranasal route. scRNA-Seq analysis of T helper cells in the airways pinpointed a unique gene signature for TH17 cells. Analysis of T-cell receptors depicted a high frequency of clones that were shared between TH17, TH2 and suppressive Treg cells, indicative of a common differentiation trajectory for these subsets.

ORGANISM(S): Mus musculus

PROVIDER: GSE244722 | GEO | 2023/10/05

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| S-EPMC3652036 | biostudies-literature
2010-10-19 | E-GEOD-24756 | biostudies-arrayexpress
| PRJEB2162 | ENA
| PRJEB20845 | ENA
2009-05-06 | GSE14999 | GEO
2018-10-10 | GSE121027 | GEO
| PRJNA1024448 | ENA
2014-11-20 | GSE63439 | GEO
2024-10-18 | GSE252908 | GEO
| PRJNA649402 | ENA