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Multi-omics profiling of PcG proteins and related factors in Drosophila cell lines [Micro-C]

ABSTRACT: To understand the combinatorial binding of different PcG proteins and their binding dynamics across cell types, we performed multi-omics profiling in three Drosophila cell lines, including S2, Kc167 and/or D17-c3 cells. The profiled data included: 1) RNA-seq; 2) ATAC-seq; 3) ChIP-seq of multiple PcG proteins and other related proteins, including E(z), GAGA, Pc, Pcl, Ph, Psc, Scm, Sfmbt, Pho, Spps; 4) Multiple active and repressive histone modifications, including H3K27ac, H3K27me3, H3Krme2, H3K4me3, H3K36me2, H3K36me3; 5) Micro-C data.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE246517 | GEO | 2023/11/14

REPOSITORIES: GEO

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