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Methylomic signatures of tau and beta amyloid in transgenic mouse models of Alzheimer’s disease neuropathology [HorvathMammalMethylChip40 Methylation Beadchip]

ABSTRACT: We identified widespread DNA methylation changes associated with the development of both tau and amyloid neuropathology, including differentially methylated positions (DMPs) and regions (DMRs) at loci previously implicated in AD and overlapping changes identified in our ongoing analyses of human post-mortem AD brains.

ORGANISM(S): Mus musculus Rattus norvegicus Homo sapiens

PROVIDER: GSE246559 | GEO | 2024/10/30

REPOSITORIES: GEO

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