Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Fusobacterium nucleatum infection modulates the transcriptome and epigenome of colon cancer cells in an oxygen-dependent manner [ChIP-seq]

ABSTRACT: We studied how Fusobacterium nucleatum infection under hypoxia regulated the epigenome and transcriptome of colon cancer cells. The six datasets that are described in this study are labeled as follows: (a) Normoxia - No Bacteria (NN), (b) Normoxia - infection with Fnn (NF), (c) Normoxia - infection with E. coli (NE), (d) Hypoxia - No Bacteria (HN), (e) Hypoxia - infection with Fnn (HF), and (f) Hypoxia - infection with E. coli (HE).

ORGANISM(S): Homo sapiens

PROVIDER: GSE246614 | GEO | 2024/02/07

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Fusobacterium nucleatum infection modulates the transcriptome and epigenome of colon cancer cells in an oxygen-dependent manner [RNA-seq]

Project description:We studied how Fusobacterium nucleatum infection under hypoxia regulated the epigenome and transcriptome of colon cancer cells. The six datasets that are described in this study are labeled as follows: (a) Normoxia - No Bacteria (NN), (b) Normoxia - infection with Fnn (NF), (c) Normoxia - infection with E. coli (NE), (d) Hypoxia - No Bacteria (HN), (e) Hypoxia - infection with Fnn (HF), and (f) Hypoxia - infection with E. coli (HE).

2024-02-07 | GSE246615 | GEO

Comparison of Fusobacterium Nucleatum stimulated and unstimulated neutrophils

Project description:Neutrophils are known to be stimulated by different periodontal bacteria to produce reactive oxygen species and cytokines. It is inportant to investigate the gene changes made by bacteria of importance, of which, for periodontal disease, fusobaterium nucleatum is one. we used microarrays to investigate gene experssion changes in peripheral blood neutrophils werwhich e stimulated with or with out Fusobacterium Nucleatum (10953). Neutrophils from periodonatlly healthy individuals (n=4) were isolated and stimulated for 3hrs with or without fusobaterium nucleatum (10953). RNA was then extracted from these and pooled before hybridization on Affymetrix microarrays

2010-07-20 | E-GEOD-20151 | biostudies-arrayexpress

Comparison of Fusobacterium Nucleatum stimulated and unstimulated neutrophils

2010-07-20 | GSE20151 | GEO

Translatome Hypoxia-Acidosis, TMT-pulse SILAC

Project description:Cells were grown in light (R0K0) SILAC media (AthenaES) for 7 days, they were then incubated in light media for 24 hours in respective condition (normoxia neutral (NN) pH: 7.4; hypoxia neutral (HN)1% O2, pH: 7.4; hypoxia acidosis (HA), 1% O2, pH=6) and pulsed with heavy (R10K8) SILAC media (AthenaES) for 16 hr (TMT-pSILAC) following treatment.

2020-09-28 | PXD015643 | Pride

Effect of Fusobacterium nucleatum on human HUVEC cells

Project description:Localization of Fusobacterium nucleatum in the placenta may be associated with pregnancy complications including preeclampsia (PE), but its specific pathobiology is unknown. Our aim was to analyze the effect of Fusobacterium nucleatum on HUVEC cells to further elucidate placental dysfunction in the context of Fusobacterium nucleatum infestation.

2024-06-08 | GSE269085 | GEO

Fusobacterium nucleatum intraoral infection and periodontitis in C57BL/6J mice

Project description:Individual miRNA analyzed were successfully constructed through NanoString technology of a total of 577 mouse miRNAs in 20 number of SHAM mice and 20 number of Fusobacterium nucleatum infected mice, which have been euthanized on the end of 16 weeks infection study.

2023-12-04 | GSE248487 | GEO

RNA landscape of the emerging cancer bug Fusobacterium nucleatum

Project description:Analysis of the region of interest for total protein samples or the outer membrane fraction of Fusobacterium nucleatum subsp. nucleatum ATCC 23726. The bacteria carried either an empty vector control, or a plasmid for the overexpression of the FoxI sRNA or its mutant version FoxI-3C.

2021-05-04 | PXD022474 | Pride

Fusobacterium nucleatum

Project description:Fusobacterium nucleatum Genome sequencing

| PRJNA831657 | ENA

Fusobacterium nucleatum

Project description:Fusobacterium nucleatum Genome sequencing

| PRJNA932162 | ENA

Fusobacterium nucleatum

Project description:Fusobacterium nucleatum Genome sequencing

| PRJNA923398 | ENA