Transcriptomics

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MRNA expression data from iPSCs, ntESCs and iPSC-nt-ESCs


ABSTRACT: We generated three kinds of genetically identical mouse reprogrammed cells: induced pluripotent stem cells (iPSCs), nuclear transfer embryonic stem cells (ntESCs) and iPSC-nt-ESCs that are established after successively reprogramming of iPSCs by nuclear transfer (NT). NtESCs show better developmental potential than iPSCs, whereas iPSC-nt-ESCs display worse developmental potential than iPSCs. We used microarrays to distinguish the gene expression differences among three pluriptoent stem cells and identified that imprinted genes had a similar expression pattern in iPSCs and iPSC-nt-ESCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE24705 | GEO | 2011/05/31

SECONDARY ACCESSION(S): PRJNA132319

REPOSITORIES: GEO

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