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Transcriptome-wide mapping of RNA secondary structure ensembles in a living cell


ABSTRACT: RNA molecules can populate an ensemble of alternative structural conformations, but the true extent of the RNA secondary structure folding space of a living cell has never been explored. We here generated the first transcriptome-wide maps of RNA secondary structure ensembles in Escherichia coli, both at physiological temperature and upon cold-shock. Our analysis revealed hundreds of novel putative conserved RNA switches.

ORGANISM(S): Escherichia coli

PROVIDER: GSE247244 | GEO | 2024/09/24

REPOSITORIES: GEO

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