Transcriptomics

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Changes in WT C2C12 Mouse Muscle Myoblast gene expression throughout differentiation.


ABSTRACT: Genesis of skeletal muscle relies on the differentiation and fusion of mono-nucleated muscle progenitor cells into the multi-nucleated muscle fiber syncytium. The temporally-controlled cellular and morphogenetic changes underlying this process are initiated by a series of highly coordinated transcription programs. Ultimately, highly specific coordination of these transcription programs is critical for their masterfully timed transitions, which in turn facilitate the intricate generation of skeletal muscle fibers from a naïve pool of progenitor cells. This work aims to categorize changes of gene expression in vitro in C2C12 mouse muscle myoblasts while they begin to form these multinucleated myotubes.

ORGANISM(S): Mus musculus

PROVIDER: GSE247438 | GEO | 2024/04/03

REPOSITORIES: GEO

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